Bruneck is the largest town in the Puster valley

Bruneck lies at the confluence of the Ahr with the Rienz, which itself flows into the Eisack river. Here the northern Tauferer Ahrntal side valley and the southern Gadertal (Val Badia) of the Gran Ega creek join the broad Pustertal. The municipal area stretches from the slopes of the Zillertal Alps in the west to the Rieserferner Group of the High Tauern range in the east. In the south rises the Kronplatz massif, part of the Dolomites, the Bruneck Hausberg with the Messner Mountain Museum Corones building designed by Zaha Hadid on top at an elevation of 2,275 metres (7,464 ft) and a popular ski area.

The Bruneck town centre is located about 35 kilometres (22 mi) west of Brixen and 70 kilometres (43 mi) of the regional capital Bolzano on the road to the Brenner Pass. To the east, the town is 60 kilometres (37 mi) from Winnebach (part of Innichen) on the border with East Tyrol in Austria.